Centre Hannah Jones will captain a Wales side that includes 14 players in the starting line-up who have featured in wins against Ireland and Scotland in this campaign.
The front row of Gwenllian Pyrs, Kelsey Jones and Sisilia Tuipulotu are back to face Italy, with flanker Alex Callender returning in the backrow.
Wales skipper Hannah Jones
Keira Bevan returns at scrum-half to partner fly-half Elinor Snowsill, while Lleucu George keeps her place at centre.
Wing Ameila Tutt is set to make her Wales debut off the bench and will become the fourth player to win her first cap during this Six Nations campaign.
Centre Kerin Lake is selected on the bench, being declared fit after recovering from a calf injury picked up against Scotland.
Ioan Cunningham, Wales head coach, said:
“Our goal at the start of the TikTok Six Nations was to have two wins heading into the final game against Italy. We have made no secret of the fact that we have targeted three wins in this tournament.
25.04.23 – Wales Women Rugby Training Session – Wales head coach Ioan Cunningham during a training session at Parma Rugby Club ahead of the Tik Tok Six Nations match against Italy
“The players, coaches and staff have all worked extremely hard to get us to where we are now with the final game to play, and we know we have made significant strides during this tournament.
“We have shown against two of the best sides in the world, England and France, that we can compete with the best, but know we need an 80 minute performance in Parma.
“Amelia Tutt will become our fourth new cap during this campaign and has earned her place in the squad and having an experienced player like Kerin return to the squad is a major boost.
“Italy have won the last two games against us and are two places above us in the world rankings but we are excited about the challenge ahead of us.
“We are where we wanted to be, facing Italy on their home turf.”
Wales Women’s Senior team to face Italy in the 2023 TikTok Six Nations
15. Courtney Keight (Bristol Bears)
14. Lisa Neumann (Gloucester Hartpury)
13. Hannah Jones (capt, Gloucester Hartpury)
12. Lleucu George (Gloucester Hartpury)
11. Carys Williams- Morris (Loughborough Lightning)
10. Elinor Snowsill (Bristol Bears)
9. Keira Bevan (Bristol Bears)
1.Gwenllian Pyrs (Bristol Bears)
2. Kelsey Jones (Gloucester Hartpury)
3. Sisilia Tuipulotu (Gloucester Hartpury)
4. Abbie Fleming (Exeter Chiefs)
5. Georgia Evans (Saracens)
6. Bethan Lewis (Gloucester Hartpury)
7. Alex Callender (Worcester Warriors)
8. Sioned Harries (Worcester Warriors)
Replacements
16. Carys Phillips (Worcester Warriors)
17. Caryl Thomas (Bristol Bears)
18. Cerys Hale (Gloucester Hartpury)
19. Bryonie King (Bristol Bears)
20. Kate Williams (Gloucester Hartpury)
21. Ffion Lewis (Worcester Warriors)
22. Kerin Lake (Gloucester Hartpury)
23. Amelia Tutt (Loughborough Lightning)
