Saturday’s game will be the first Wales home clash with a crowd in 15 months.
It will be something some of the players have never experienced before.
“It is sad some people have won first caps and had massive experiences while friends and family can’t be there,” said Humphreys.
“At least people having their first caps now can have their friends and family there. That’s a positive.
“It’s massive for us. You go back to the autumn and we’re playing outside of the stadium because it was a field hospital.
“Now, with crowds of 8,200 people will still make a lot of noise for us.”
This summer’s clashes with Canada and Argentina gives an opportunity for Wales head coach Wayne Pivac to analyse the next generation.
There are five new faces in the Wales squad and one of those is Ben Carter of the Dragons.
Humphreys has been really pleased with the 20-year-old lock’s form in recent months.
“First off, it’s been great seeing him in the camp,” added Humphreys.
“I’ve watched him over the last couple of months this season and I’ve been really impressed with him.
“Physically, he can compete at this level and that’s the first thing you look for. It’s been a lot of learning for him. He’s calling line-outs for us on his first cap which is a big ask for him.”
Another positive for Wales is the return of the experienced Ross Moriarty.
“He was a big player for us in the Six Nations before last. He played really well for us, but he’s picked up a few injuries along the way,” said Humphreys.
“He’s a big player for us going forward so to have him back around the group gives us a real physicality and we’re hoping he goes well on the weekend.”
Jonathan Davies will captain the team on Saturday. Humphreys has been delighted with the influence he has had on the young players in the squad.
“He’s been brilliant. With him captaining the team he’s had a really good influence on the new boys coming in.
“There are a few boys in here who have been here before.
“That’s good, but it’s tempered with a lot of learning for these [new] boys.
“It’s an education of speed, intensity and the learning that goes along with being in an international camp because you have such a short period of time to get up to speed.”
Canada have not played a game since the last World Cup so Humphreys is looking for the squad to prepare for all eventualities.
