Jenkins will make his 16th appearance in the game’s showpiece tournament and will line-up alongside Scott Baldwin and Tomas Francis in the front-row. Bradley Davies and Alun Wyn Jones pack down in the second-row.
Captain Sam Warburton packs down in an all British and Irish Lions back-row with Dan Lydiate and Taulupe Faletau.
Gareth Davies and Dan Biggar are named at half-back with Jamie Roberts and Scott Williams partnering in the centre.
The back-three sees Liam Williams at full-back with George North and Hallam Amos on the wings.
“Saturday is a huge occasion for both teams and for the tournament and we are really looking forward to it,” said Wales Head Coach Warren Gatland.
“Both sides kicked their tournament off with a bonus-point win but we know we will need to step up at Twickenham on Saturday.”
Ken Owens, Aaron Jarvis and Samson Lee are the front-row replacements, with Luke Charteris and Justin Tipuric completing the forwards contingent. Lloyd Williams, Rhys Priestland and Alex Cuthbert are named as the backs replacements.
WALES TEAM TO PLAY ENGLAND:
Liam Williams, George North, Scott Williams, Jamie Roberts, Hallam Amos, Dan Biggar, Gareth Davies, Gethin Jenkins, Scott Baldwin, Tomas Francis, Bradley Davies, Alun Wyn Jones, Dan Lydiate, Sam Warburton (Capt), Taulupe Faletau.
Replacements: Ken Owens, Aaron Jarvis, Samson Lee, Luke Charteris, Justin Tipuric, Lloyd Williams, Rhys Priestland, Alex Cuthbert.
